MSC for Dummies
With the idea that a far more fast cell cycle is often a critical part of pluripotency, reprogramming efficiency is often enhanced. Approaches for bettering pluripotency by manipulation of cell cycle regulators contain: overexpression of Cyclin D/Cdk4, phosphorylation of Sox2 at S39 and S253, overexpression of Cyclin A and Cyclin E, knockdown of Rb